Trans-Arterial Chemo Embolisation (DC Bead) of Metastases from a Choroid Melanoma

Jakub Wiskirchen, MD, Gunnar Tepe, MD, and Philippe L. Pereira, MD
Department for Diagnostic and Interventional Radiology University Hospital Tübingen, Germany

Patient History

Female patient (66 y) suffering from a choroid melanoma. The CT scans (Figs 1 and 2) showed multiple hypovascular metastases. Thus, initially we were asked to perform a chemoperfusion of the liver.

However, an initial angiography shaved presented the metastases to be hypervascular and it was decided to perform an arterial chemoembolisation.

Fig Fig 2

Procedure

After obtaining a survey angiography (Fig 3) using a 4Fr C2 Cobra™ (Cook®) catheter, the feeder of the metastases was catheterised with the help of a 2.7Fr microcatheter (Progreat™, Terumo®), and a total of 2ml DC Bead™ (Biocompatibles) loaded with 50mg epirubicin (Pfizer) were introduced (Fig 4 and 5).

Fig 3 Fig 4

Outcome

In the control angiography following embolisation the previously hypervascular metastases no longer opacified (Fig 6).

Fig 5 Fig 6

DC Bead Sizes and Label Colours

Bead size & label colour Volume
of
beads
Product code Time to >90% loading Time to 98% loading
100-300µm 2ml DC2V103 5 mins 20 mins
300-500µm 2ml DC2V305 10 mins 40 mins
500-700µm 2ml DC2V507 20 mins 75 mins
700-900µm 2ml DC2V709 30 mins 100 mins