Uterine Fibroid Embolisation using Bead Block

Professor J. Pelage, MD
Department of Body and Vascular Imaging, Hôpital Lariboisière, Paris, France

Patient History

  • 39-year-old woman with menorrhagia and pelvic pressure related to multiple uterine fibroids.
  • Hormonal treatment was not effective and the patient was treated with uterine artery embolisation as an alternative to hysterectomy.
Bead Block Case 10 fig 1

Pre-embolisation MRI (sagittal T2-weighted image) shows multiple uterine fibroids

Procedure

  • Bilateral uterine artery embolisation was performed with 12ml of Bead Block 700-900μm via a 2.7Fr Progreat microcatheter.
  • Angiographic end-point was near-stasis in the uterine artery with sluggish antegrade flow.

Outcome

  • Early post-embolisation procedure demonstrated complete fibroid devascularisation.
  • Three months after bilateral uterine artery embolisation, complete resolution of symptoms was observed.
  • Post-embolisation MRI confirmed marked uterine volume reduction and devascularisation of all the fibroids.

Clinician Comment

Large 700-900µm Bead Block can be easily injected through large lumen microcatheters. Targeted embolisation can be achieved.

Professor J. Pelage, MD
Hôpital Lariboisière, Paris, France

 

Bead Block Case 10 fig 2

Pre-embolisation injection into the left uterine artery demonstrates diffuse uterine hypervascularisation

Bead Block Case 10 fig 3

Post-embolisation MRI (dynamic contrast-enhanced sagittal image) performed 24 hours after embolisation shows complete devascularisation of all the fibroids

Bead Block Case 10 fig 4

Post-embolisation injection into the left uterine artery demonstrates satisfactory arterial occlusion

Regulatory notices and product safety data

Worldwide (excluding USA)

Bead Block™ is CE marked and indicated for the treatment of a variety of hypervascular tumours (including Uterine Fibroids) and arteriovenous malformations (AVMs). Bead Blockā„¢ may not be indicated for the treatment of Uterine Fibroids in your country, please check with your local distributor. For full prescribing information please refer to Bead Block instructions for use.

USA

Bead Block is intended to be used for the embolization of hypervascular tumors and arteriovenous malformations (AVMs)

Bead Block Cautions:

  • Do not use if the syringe or packaging appear damaged
  • Sterile and single use product.  Do not reuse
  • Select the size and quantity of Bead Block microspheres appropriate for the pathology to be treated
  • Embolization with Bead Block microspheres should only be performed by physicians who have received appropriate interventional occlusion training in the region intended to be embolized

For instructions for use, please refer to www.biocompatibles.com/beadblock-ifu

Bead Block Potential Complications:

  • Undesirable reflux or passage of Bead Block into normal arteries adjacent to the targeted lesion or through the lesion into other arteries or arterial beds, such as the internal carotid artery, pulmonary, or coronary circulations
  • Pulmonary embolization
  • Ischemia at an undesirable location
  • Capillary bed saturation and tissue damage
  • Ischemic stroke or ischemic infarction
  • Vessel or lesion rupture and haemorrhage
  • Neurological deficits including cranial nerve palsies
  • Vasospasm
  • Death
  • Recanalization
  • Foreign body reactions necessitating medical intervention
  • Infection necessitating medical intervention
  • Clot formation at the tip of the catheter and subsequent dislodgement