Literature

Arterial chemoembolization with drug-eluting beads for hepatocellular carcinoma: technical aspects, safety, and short-term results.

Date September 2007
Where presented Cardiovascular and Interventional Radiology Society of Europe (CIRSE)
Author(s) Bezzi M, Fanelli F, Nardis P, et al
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RF ablation combined with intra-arterial injection of drug eluting beads in the treatment of large hypovascular hepatic metastases

Date September 2007
Where presented Cardiovascular and Interventional Radiology Society of Europe (CIRSE)
Author(s) De Baere T, Deschamps F, Hakime A, et al
Resources

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Drug eluting beads in the treatment of hepatocellular carcinoma: results of two years follow-up

Date September 2007
Where presented Cardiovascular and Interventional Radiology Society of Europe (CIRSE)
Author(s) Malagari K, Hatzimichael K, Vergadis V, et al
Resources

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Radiofrequency ablation combined with Doxorubicin eluting beads arterial chemoembolization in the treatment of hepatocellular carcinoma: a pilot clinical trial

Date September 2007
Where presented Cardiovascular and Interventional Radiology Society of Europe (CIRSE)
Author(s) Lencioni R, Vignali C, Bozzi E, et al
Resources

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PRECISION TACE, of Hepatocellular Carcinoma with Drug-Eluting Beads: 62-Patient Registry

Date September 2007
Where presented Cardiovascular and Interventional Radiology Society of Europe (CIRSE) Congress - Biocompatibles / Terumo Symposium
Author(s) Professor K Malagari
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Drug-Eluting Bead Enhanced-RFA in Hepatocellular Carcinoma

Date September 2007
Where presented Cardiovascular and Interventional Radiology Society of Europe (CIRSE) Congress - Biocompatibles / Terumo Symposium
Author(s) Professor R Lencioni
Resources

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Doxorubicin eluting Beads: Efficacy and Safety in the treatment of HCC

Date April 2007
Where presented American Hepato Pancreato Biliary Association Meeting (AHPBA)
Author(s) Imagawa, D
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Pilot Study with Intra-arterial Doxorubicin-Eluting Microspheres (GelSpheres) in Patients with Unresectable HCC

Date March 2007
Where presented Society of Interventional Radiology (SIR)
Author(s) Kamel IR, et al
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Using Epirubicin-loaded DC Bead for Superselective Embolisation of Hepatocellular Carcinoma: Initial Experiences

Date March 2007
Where presented Society of Interventional Radiology (SIR)
Author(s) Wiskirchen, et al
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Transarterial Chemoembolisation of Hepatocellular Carcinoma (HCC) with Drug Eluting Beads

Date March 2007
Where presented Society of Interventional Radiology (SIR) 23th Annual Scientific Meeting
Author(s) Malagari K, et al
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Combined RF Ablation and Doxorubicin Eluting Bead Chemoembolisation in Hepatocellular Carcinoma

Date March 2007
Where presented Society of Interventional Radiology (SIR)
Author(s) Lencioni R, et al
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Efficacy and Safety of Doxorubicin-eluting beads in the treatment of HCC

Date January 2007
Where presented Gastrointestinal Cancers Symposium (ASCO GI)
Author(s) Yamamoto M, et al
Resources

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Drug loaded microspheres for precise transarterial chemoembolisation of hypervascular liver lesions

Date November 2006
Where presented Interventional News, Educational Supplement
Author(s) Wiskirchen J, Tepe G, Pereira P
Resources

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Review of Abstracts and presentations on Drug-Eluting Beads

Date November 2006
Where presented Interventional News, Educational Supplement
Author(s) DeBaere T, Stadler A, Bruix J, Malagari K, Llovet J M, Pelage J P
Resources

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The future of interventional oncology

Date November 2006
Where presented Interventional News, Educational Supplement
Author(s) Vogl T, Lencioni R (CIRSE 2006)
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Chemoembolisation of Hepatocellular Carcinoma with Drug Eluting Beads reduces the systemic availability of Doxorubicin. A pharmacokinetic assessment.

Date 2006
Where presented American Association for Cancer Research (AACR)
Author(s) Varela M
Resources

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Transcatheter Arterial Chemoembolisation (TACE) for HCC - Classic Concepts and Future Evolution

Journal European Oncological Disease
Date 2006
Author(s) Liapi E, Geschwind J
Resources

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Clinical experience with Drug Eluting Beads for Chemoembolisation of Unresectable HCC

Date 2005
Where presented Cardiovascular and Interventional Radiology Society of Europe (CIRSE)
Author(s) Lammer J
Resources

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Single Centre, Prospective Study, Designed to Assess the Clinical Performance of DC Bead loading with Doxorubicin in the primary treatment of Unresectable HCC by Chemoembolisation

Date 2005
Where presented Society of Interventional Radiology (SIR)
Author(s) Lammer J
Resources

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New Intraarterial Drug Delivery System for Liver Cancer: Evaluation of Pharmacokinetics

Date 2004 / 2005
Where presented Radiological Society of North America (RSNA) / American Society of Clinical Oncology (ASCO)
Author(s) Geschwind J
Resources

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Regulatory notices and product safety data

Worldwide (excluding USA and Canada)

DC Bead® is CE marked and is indicated for the treatment of malignant hypervascular tumours and loading with doxorubicin drug. DC Bead® is also indicated for loading with irinotecan for the treatment of metastatic colorectal cancer (mCRC). For full prescribing information please refer to DC Bead instructions for use.

USA

DC Bead is not currently available for sale or distribution in the USA. DC Bead has not been submitted for approval to the FDA.

Canada

DC Bead® with doxorubicin is indicated for trans-arterial chemoembolization (TACE) of unresectable hepatocellular carcinoma (HCC). DC Bead are also intended to be loaded with irinotecan for the purpose of embolization of vessels supplying malignant colorectal cancer metastasised to the liver (mCRC), and delivery of a local, controlled, sustained dose of irinotecan to the mCRC. For full prescribing information please refer to DC Bead Canada Instructions for Use 

Tawain

DC Bead is approved by the Department of Health and is intended to be loaded with Mayne (Hospira) doxorubicin HCI for the purpose of embolisation of vessels supplying malignant hypervascularised tumour(s), and delivery of a local, controlled, sustained dose of doxorubicin.  DC Bead is also indicated for the embolisation of nidus vessels without medication.  Approved size ranges in Taiwan are 300-500µm and 500-700µm.