Literature

Role of slow-release doxorubicin eluting beads (DEB) transarterial chemoembolization (TACE) in the treatment of hepatocellular carcinoma (HCC).

Date 13 - 17 September 2008, Copenhagen, Denmark
Where presented Cardiovascular and Interventional Radiology Society of Europe (CIRSE)
Author(s) A Vit, M Sponza, G Piccoli et al
Resources

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Treatment of hepatocellular carcinoma with drug eluting beads versus microspheres before transplant: imaging and histology results

Date 13 - 17 September 2008, Copenhagen, Denmark
Where presented Cardiovascular and Interventional Radiology Society of Europe (CIRSE)
Author(s) A Nicolini, L Martinetti, S Crespi
Resources

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Long term results of doxorubicin loaded DC Bead in the treatment of HCC survival, recurrence free interval and quality of life

Date 13 - 17 September 2008, Copenhagen, Denmark
Where presented Cardiovascular and Interventional Radiology Society of Europe (CIRSE)
Author(s) A Vit, M Sponza, G Piccoli et al
Resources

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Evidence for drug eluting beads.

Date 13 - 17 September 2008, Copenhagen, Denmark
Where presented Cardiovascular and Interventional Radiology Society of Europe (CIRSE)
Author(s) J Lammer, J Pelage, M Wassef et al
Resources

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Drug-Eluting Beads: A Novel Neoadjuvant Treatment in Colorectal Metastases and Primary Liver Cancer

Date 12 September 2008
Where presented ESSO 2008, The Hague, The Netherlands
Author(s) Dr Julien Namur; Department of Neuroradiology, Hopital Lariboisiere, Paris, France
Resources

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Preliminary results from an open registry evaluating Drug-Eluting Beads in primary and metastatic liver tumours

Date 12 September 2008
Where presented ESSO 2008, The Hague, The Netherlands
Author(s) Dr Robert Martin; Associate Professor of Surgery, Division of Surgical Oncology, University of Louisville, Kentucky, USA
Resources

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Transarterial Chemoembolisation with Epirubicin Drug Eluting Bead versus Transarterial Embolisation before LIver Transplantation for Hepatocellular Carcinoma

Date 5 - 7 September 2008
Where presented International Liver Cander Association (ILCA), 2008
Author(s) A Nicolini, L Martinetti, S Crespi et al
Resources

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Doxorubicin-loaded LC Bead chemoembolization for HCC (PRECISION TACE): Assessment of tumor necrosis with imaging and histologic follow-up

Date 5 - 7 September 2008
Where presented International Liver Cander Association (ILCA), 2008
Author(s) S Citron, M Dupuis, E Gallardo et al
Resources

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Chemoembolization with doxorubicin-eluting beads for HCC in surgical and non-surgical candidates, with histological evidence of efficiency in transplanted patients

Date 5 September 2008, 11.15-12.30, The Fairmont Chicago Hotel
Where presented International Liver Cancer Association (ILCA), Chicago, Illinois, USA
Author(s) Dr Marty Sellers; Director, Liver Cancer Services Piedmont Hospital, Atlanta, USA
Resources

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International hepatic arterial embolization registry for hepatocellular cancer: surgical downstaging and safety

Date 5 September 2008, 11.15-12.30, The Fairmont Chicago Hotel
Where presented International Liver Cancer Association (ILCA), Chicago, Illinois, USA
Author(s) Dr Robert Martin; Associate Professor of Surgery, Division of Surgical Oncology. University of Louisville, Kentucky, USA
Resources

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Evaluation of Drug Loadable Porous Microspheres for Doxorubicin

Date 22 - 25 June 2008, Los Angeles, California
Where presented WCIO 2008 & Best of ASCO
Author(s) K Lee, E Liapi, M Buijs et al
Resources

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Precision TACE: Improved Possibilities in Fighting Liver Cancer

Date 22 - 25 June 2008, Los Angeles, California
Where presented WCIO 2008 & Best of ASCO
Author(s) A Slanic, J Matela
Resources

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Acutely Ruptured Hepatocellular Carcinoma: Should Transarterial Chemoembolization with Doxorubicin Drug-Eluting Microspheres Be the Initial Treatment of Choice?

Date 22 - 25 June 2008, Los Angeles, California
Where presented WCIO 2008 & Best of ASCO
Author(s) T H Nguyen, D Liu, D Imagawa
Resources

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Biology and Advances in Drug-Eluting Beads

Date 22 - 25 June 2008
Where presented WCIO & Best of ASCO 2008
Author(s) Dr Peter Stratford
Resources

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Product Assessment and Expanded Opportunities in Embolotherapy

Date 7 June 2008, Barcelona, Spain
Where presented GEST 2008 Satellite Symposium
Author(s) Dr Thierry De Baere, Institut de Cancerologie Gustave Roussy, Villejuif, France
Resources

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Transarterial chemoembolization (TACE) with doxorubicin eluting beads (DEB) for the treatment of hepatocellular carcinoma (HCC)

Date 30 May - 3 June 2008, Chicago, USA
Where presented American Society of Clinical Oncology (ASCO)
Author(s) A. Vit, F. De Pauli, M. Sponza, et al
Resources

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Interim Analysis of DC/LC Bead Open Surgical Registry in Primary and Metastatic Liver Tumours

Date 10 April 2008, Florence, Italy
Where presented ET/ECIO Satellite Symposium
Author(s) Dr Robert MARTIN, University of Kentucky, Lexington, USA
Resources

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TACE with DC Bead as a pre-transplant treatment for HCC: results with anatomopathological data

Where presented ET/ECIO Satellite Symposium
Author(s) Professor Pierre GOFFETTE, Cliniques Universitaires de St Luc, Brussels, Belgium
Resources

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TACE with DC Bead as a pre-transplant treatment for HCC: results with anatomopathological data

Date 10 April 2008
Where presented ET/ECIO Satellite Symposium
Author(s) Professor Pierre GOFFETTE, Cliniques Universitaires de St Luc, Brussels, Belgium
Resources

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DC Bead for the Pathological Downstage of HCC to Transplant: A Case History

Date April 2008, Barcelona, Spain
Where presented ET/ECIO 2008
Resources

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Regulatory notices and product safety data

Worldwide (excluding USA and Canada)

DC Bead® is CE marked and is indicated for the treatment of malignant hypervascular tumours and loading with doxorubicin drug. DC Bead® is also indicated for loading with irinotecan for the treatment of metastatic colorectal cancer (mCRC). For full prescribing information please refer to DC Bead instructions for use.

USA

DC Bead is not currently available for sale or distribution in the USA. DC Bead has not been submitted for approval to the FDA.

Canada

DC Bead® with doxorubicin is indicated for trans-arterial chemoembolization (TACE) of unresectable hepatocellular carcinoma (HCC). DC Bead are also intended to be loaded with irinotecan for the purpose of embolization of vessels supplying malignant colorectal cancer metastasised to the liver (mCRC), and delivery of a local, controlled, sustained dose of irinotecan to the mCRC. For full prescribing information please refer to DC Bead Canada Instructions for Use 

Tawain

DC Bead is approved by the Department of Health and is intended to be loaded with Mayne (Hospira) doxorubicin HCI for the purpose of embolisation of vessels supplying malignant hypervascularised tumour(s), and delivery of a local, controlled, sustained dose of doxorubicin.  DC Bead is also indicated for the embolisation of nidus vessels without medication.  Approved size ranges in Taiwan are 300-500µm and 500-700µm.